Overview

Mesenchymal Stromal Cells as Tumor Stromal Modulators provides the latest data on the heterogeneous cell population, reporting on topics such as immunomodulating, tissue repairing, differentiating, and their migratory and angiogenic abilities that make them important tools for clinical and translational research. An understanding of the role of MSCs in modulating tumor growth provides a glimpse into their role in non-pathological tissue remodeling and potential regenerative tissue therapies. The book is a comprehensive source for the n understanding of the role of MSCs as ubiquitous connective tissue cell components which may have both direct and indirect effects on the tumor microenvironment and potential for regenerative therapeutics for various diseases. Using cancer as a model disease, this book explores the transformative role MSCs play in the recruitment of disease cells, cell repair, and immunological defenses. Explores the biology of Mesenchymal Stromal Cells (MSCs) and tissue related function Discusses the bidirectional communication between tumor stroma and MSCs derived from bone marrow, adipose tissue, and other tissue types Provides in-depth analysis of the effects of MSCs on key processes that regulate disease progression, such as angiogenesis, metastatic potential, invasion, proliferation, and tumor immune privileges