Overview
I. Clinical Impact of Sex Steroids on Growth Hormone Secretion.- 1. Sex-Steroid-Growth Hormone Axis Interactions in Normal Female Puberty.- 2. Sex-Steroid-Growth Hormone Interactions During Normal Male Puberty.- 3. Impact of Testosterone Replacement on the Maturation of the Growth Hormone-IGF-I Axis.- 4. Sex-Steroid -Hormone Modulation of the Somatotropic Axis During Normal Male Puberty.- 5. Influence of Testosterone on the GH-IGF-I Axis in Healthy Elderly Men.- 6. Effect of Estrogen on GH Secretion and Action in Postmenopausal Women.- 7. Menstrual Cycle Interaction with the Growth Hormone Axis.- 8. Growth Hormone Axis Response to Superovulation.- 9. Androgenic Modulation of the Growth Hormone-IGF Axis and Its Impact on Metabolic Outcomes.- 10. Proposed Mechanisms of Sex-Steroid-Hormone Neuromodulation of the Human GH-IGF-1 Axis.- 11. The Growth Hormone Axis in Precocious Puberty.- II. Sex Steroids and GHRH-Somatostatin.- 12. Hypothalamic Control Mechanisms of Sexually Dimorphic Growth Hormone Secretory Patterns in the Rat..- 13. Sex Differences in Growth Hormone-Releasing Hormone (GHRH) and Somatostatin Neurons.- 14. Sex-Steroid Interaction with Somatostatin and GHRH in the Rat.- 15. Sex-Steroid Effects on Primate Somatotrophs.- 16. Sex-Steroid Effects on Perifused Pituitary.- 17. Somatotrope Heterogeneity and Its Involvement in Growth Hormone (GH) Regulation.- III. How Sex Steroids Modulate GH Action on Target Tissues.- 18. Sex-Steroid and GH Interactions in the Regulation of Lipid Metabolism.- 19. Estrogen Replacement Therapy and the Response to Human Growth Hormone.- 20. Influence of Gender on Response to Growth Hormone Substitution Therapy in Adults with Growth Hormone Deficiency.- 21. How Sex Steroids Modulate GH Action on Target Tissues: Long-Term Follow-up in GH-Deficient Adults.- 22. Growth Hormone Treatment in Turner Syndrome: Rationale for Therapy.- 23. Practical Issues of Clinical Growth Hormone Therapy in Turner Syndrome.- IV. GH Secretagogues: Differential Effects in Men and Women.- 24. Influence of Gonadal Function on GH Secretion.- 25. Endocrine Responses to GH Secretagogues in Relation to Sex and Age in Humans.- 26. Gender Impact on the GH Response to Exercise.- 27. Stimulated Release of GH in Normal Younger and Older Men and Women.- V. Novel Techniques in Investigating the Reproductive and GH Axis.- 28. Genetic and Transgenic Models to Investigate the Growth Hormone Axis and Sexual Dimorphism.- 29. Estrogen Receptor Expression in the Pituitary Gland.- 30. Metabolic Effects of GH/IGF-I, Testosterone, and Estrogen: Studies in Children and Adults.- 31. Innovative Quantitative Neuroendocrine Techniques.- 32. Sexual Dimorphism of Liver Cytochrome P-450 Gene Expression: GH Pulse-Activated STAT Signaling Mechanisms.- 33. Intracellular Signaling Networks.- Author Index.
- | Author: Johannes D. Veldhuis
- | Publisher: Springer
- | Publication Date: Aug 19, 1999
- | Number of Pages: 384 pages
- | Binding: Hardback or Cased Book
- | ISBN-10: 0387988106
- | ISBN-13: 9780387988108
