Single-Particle Cryoem Of Biological Macromolecules (Biophysical Society)

This edited book is written for students, postdocs and established investigators who want to enter the field of single-particle cryo-EM. This is a recently developed method to determine high-resolution structures of biological macromolecules. A major strength is the fact that cryo-EM does not require prior crystallization of protein complexes. It is especially well suited for larger complexes and molecular machines. This book, provides a comprehensive, accessible and authoritative introduction to the field. It covers all necessary background, ranging from the underlying concepts to practical aspects such as specimen preparation, data-collection, data analysis, and the final validation of results. Key features Written for students, postdocs and established investigators who want to enter the field of single-particle cryo-EM Provides a comprehensive, accessible and authoritative introduction to the field of high-resolution structure analysis by single-article cryo-EM Covers all necessary background, ranging from the underlying concepts to practical aspects such as specimen preparation, data-collection, data analysis, and the final validation of results Authors of individual sections of this book have been recruited from among the most authoritative leaders in each topic

• | Author: Glaeser, Eva Nogales, Wah Chiu
• | Publisher: Iop Publishing Ltd
• | Publication Date: May 19, 2021
• | Number of Pages: 120 pages
• | Language: English
• | Binding: Hardcover
• | ISBN-10: 0750330376
• | ISBN-13: 9780750330374