Tgf-ß Signaling: Methods And Protocols (Methods In Molecular Biology, 1344)
Humana
ISBN13:
9781493949939
$139.06
This volume details up-to-date information and attempts to take the reader into the exciting realm of TGF-ß from the basic principles to the practical applications. Chapters provide basic introduction of TGF-ß signaling from the cell surface to the nucleus, methods and techniques for the investigation of TGF-ß signaling mechanism including receptors, Smads, intracellular kinases, microRNA, epigenetic regulation, post-translational regulations, non-Smad pathway; the physiological implications including those in cell cycle arrest, epithelial-mesenchymal transition, endothelial cells, adipogenesis, Th differentiation, stem cell, bone remodeling, ovary, zebrofish development, and frog animal capping; and the methodologies including metastasis imaging, 3D morphogenesis, membrane receptor quantification, conditional knockout, bone remodeling, kinase and phosphatase assays, BiFC interaction assays, and genome-wide siRNA screen. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, TGF-Beta Signaling: Methods and Protocols aims to ensure successful results in the further study of this vital field.
- | Author: Xin-Hua Feng|Pinglong Xu|Xia Lin, Xin-Hua Feng
- | Publisher: Humana
- | Publication Date: Aug 23, 2016
- | Number of Pages: 406 pages
- | Language: English
- | Binding: Paperback/Science
- | ISBN-10: 1493949934
- | ISBN-13: 9781493949939
- Author:
- Xin-Hua Feng|Pinglong Xu|Xia Lin, Xin-Hua Feng
- Publisher:
- Humana
- Publication Date:
- Aug 23, 2016
- Number of pages:
- 406 pages
- Language:
- English
- Binding:
- Paperback/Science
- ISBN-10:
- 1493949934
- ISBN-13:
- 9781493949939