Overview
Why the Spike protein is relevant for COVID19 therapeutics Whole genome mutation rates Phylogenetic systems Mechanism of immune escape: single nucleotide mutations, insertion/deletions, and recombination. Spike protein mutations detected in currently circulating strains. SARS-CoV-2 variants B.1.1.298 B.1.1.7 (alpha) B.1.351 (beta) B.1.1.28- and B.1.1.33-derived Brazilian variants (including gamma and zeta) B.1.525 (eta) B.1.526 (iota) B.1.427/B.1.429 (epsilon) B.1.617-derived variants (including kappa and delta) B.1.617.1 Delta VOC C.37 (lambda) P.3 (theta) Other variants under monitoring (VUM) Which strain will finally become dominant? SARS-CoV-2 variants characterization Predicting the functional consequences of mutations Efficacy of vaccines and monoclonal antibodies against SARS-CoV-2 variants Selective pressures exerted by antibody-based therapeutics
- | Author: Daniele Focosi
- | Publisher: Springer
- | Publication Date: Nov 12, 2021
- | Number of Pages: 136 pages
- | Language: English
- | Binding: Paperback
- | ISBN-10: 3030873234
- | ISBN-13: 9783030873233
