Overview

1. Physiology of the GABA and Glycine System. 2. The Molecular Architecture of GABA A Receptors. 3. Pharmacology and Pathophysiology of GAB A-Receptor Subtypes by Genetic Dissection. 4. Steroid Modulation of GABA A Receptors. 5. Allosteric Modulation of GABA A Receptor Function by General Anesthetics and Alcohols. 6. Anticonvulsants Acting on the GABA-System. 7. Heterologous Regulation of GABA A Receptors: Protein Phoyphorylation. 8. Tolerance and Dependence to Ligands of the Benzodiazepine Recognition Sites Expressed by GABA A Receptors. 9. GABA A Receptors and Disease. 10. GABA C Receptors: Structure, Function and Pharmacology. 11. Structure of GABA B Receptors. 12. Pharmacology of GABA B Receptors. 13. GABA B Receptor Signaling Pathways. 14. Structure and Function of GABA Transporters. 15. Pharmacology of GABA Transporters. 16. Structures, Diversity and Pharmacology of Glycine Receptors and Transporters.