Overview

COVID-19, the current pandemic, is a contagious respiratory disease caused by the SARS-CoV-2 retrovirus, which mainly leads to acute respiratory distress syndromes and pneumonitis. Furthermore, frail and polymorbid individuals are at greater risk of developing severe forms of COVID-19, including patients with type 2 diabetes.The aim of our study is to highlight the relationship between T2DM and COVID-19 and to decipher the various pathophysiological mechanisms involved by answering the following questions: Why do diabetics have a higher mortality rate than non-diabetics? How can all this be explained at the molecular level? What are the pathophysiological mechanisms involved? Are anti-COVID-19 treatments safe for diabetic patients? Does SARS-CoV-2 cause diabetes?