Overview
This publication details the isolation of proteins from biological materials, techniques for solid-liquid separation, concentration, crystallization, chromatography, scale-up, process monitoring, product formulation, and regulatory and commercial considerations in protein production. The authors discuss the release of protein from a biological host, selectivity in affinity chromatography, precipitation of proteins (both non-specific and specific), extraction for rapid protein isolation, adsorption as an initial step for the capture of proteins, scale-up and commercial production of recombinant proteins, and process monitoring in downstream processing.
- | Author: Rajni Hatti-Kaul
- | Publisher: CRC Press
- | Publication Date: Feb 05, 2003
- | Number of Pages: 676 pages
- | Binding: Hardback or Cased Book
- | ISBN-10: 0824707265
- | ISBN-13: 9780824707262
