Isolation and Purification of Proteins (Biotechnology and Bioprocessing)

This publication details the isolation of proteins from biological materials, techniques for solid-liquid separation, concentration, crystallization, chromatography, scale-up, process monitoring, product formulation, and regulatory and commercial considerations in protein production. The authors discuss the release of protein from a biological host, selectivity in affinity chromatography, precipitation of proteins (both non-specific and specific), extraction for rapid protein isolation, adsorption as an initial step for the capture of proteins, scale-up and commercial production of recombinant proteins, and process monitoring in downstream processing.

• | Author: Rajni Hatti-Kaul, Bo Mattiasson
• | Publisher: Crc Press
• | Publication Date: Jun 19, 2019
• | Number of Pages: 676 pages
• | Language: English
• | Binding: Paperback
• | ISBN-10: 0367395495
• | ISBN-13: 9780367395490