Exon Skipping And Inclusion Therapies: Methods And Protocols (Methods In Molecular Biology, 1828)

This book presents a comprehensive collection of detailed state-of-the-art exon skipping and splices modulation protocols. Chapters detail 14 genetic diseases, AON-mediated therapies, and CRISPR/Cas9-mediated gene editing therapies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Exon Skipping and Inclusion Therapies: Methods and Protocols aims to help researchers initiate the development of next-generation therapies.

• | Author: Toshifumi Yokota|Rika Maruyama, Toshifumi Yokota
• | Publisher: Humana
• | Publication Date: Sep 01, 2018
• | Number of Pages: 584 pages
• | Language: English
• | Binding: Hardcover/Medical
• | ISBN-10: 1493986503
• | ISBN-13: 9781493986507