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Brca1 And Brca2 Mutations - Diagnostic And Therapeutic Implications
Intechopen
ISBN13:
9781803568065
$129.00
$122.40
Mutations in the BRCA1/2 genes are the most common cause of hereditary breast and ovarian cancer (HBOC), and HBOC is an autosomal dominant cancer predisposition syndrome. Individuals with HBOC have a high risk for breast and ovarian cancers and a moderate risk for other cancers, such as prostate, pancreatic, melanoma, and fallopian tube cancers. The goal of screening individuals at high risk of familial cancer is either prevention (such as a change in lifestyle or diet) or early detection of cancer. The identification of BRCA mutation carriers is important, since increased surveillance, drug therapy, and prophylactic surgery can reduce cancer-related morbidity and mortality. In recent years, there has been substantial development in BRCA-associated hereditary breast and/or breast-ovarian cancer research and its clinical applications. In this context, this book consolidates the recent advances in BRCA-related cancer biology and therapeutics, covering a wide spectrum of interrelated topics. Chapters cover a wide range of topics, such as BRCA discovery, BRCA structure and function, BRCA-associated cancers, BRCA genetic testing and counselling, and more. This book is a valuable resource not only for medical and allied health students but also for researchers, clinical and nurse geneticists, genetic counselors, and physician assistants.
- | Author: Mani T. Valarmathi
- | Publisher: Intechopen
- | Publication Date: Jan 18, 2023
- | Number of Pages: 134 pages
- | Language: English
- | Binding: Hardcover
- | ISBN-10: 1803568062
- | ISBN-13: 9781803568065
- Author:
- Mani T. Valarmathi
- Publisher:
- Intechopen
- Publication Date:
- Jan 18, 2023
- Number of pages:
- 134 pages
- Language:
- English
- Binding:
- Hardcover
- ISBN-10:
- 1803568062
- ISBN-13:
- 9781803568065