Applications Of Minimally Invasive Nanomedicine-Based Therapies In 3D In Vitro Cancer Platforms (Synthesis Lectures On Materials And Optics) - 9783031012600

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Minimally invasive techniques such as Photodynamic Therapy (PDT) and Photochemical Internalisation (PCI) have for years been under investigation for the treatment of solid cancers. A significant number of the recent research studies have applied PDT and PCI to biological three-dimensional (3D) cancer platforms with many of the studies also involving the use of nanoparticles in order to enhance the efficacy of these light-based therapies. Interest in the employment of 3D cancer platforms has increased considerably due to the ability of the platforms to mimic in vivo models better than the conventional two-dimensional (2D) cultures. Some of the advantages of the 3D cancer systems over their 2D counterparts include improved interaction between cancer cells and the surrounding extracellular matrix (ECM) as well as restricted drug penetration which would allow optimization of treatments prior to undertaking of in vivo studies. The different chapters of this book will discuss photosensitizers and nanoparticles used in PDT and PCI in addition to the applications of these treatments in various 3D cancer models.


  • | Author: Layla Mohammad-Hadi, Marym Mohammad-Hadi
  • | Publisher: Springer
  • | Publication Date: Oct 26, 2020
  • | Number of Pages: 112 pages
  • | Language: English
  • | Binding: Paperback
  • | ISBN-10: 3031012607
  • | ISBN-13: 9783031012600
Author:
Layla Mohammad-Hadi, Marym Mohammad-Hadi
Publisher:
Springer
Publication Date:
Oct 26, 2020
Number of pages:
112 pages
Language:
English
Binding:
Paperback
ISBN-10:
3031012607
ISBN-13:
9783031012600