The Effects Of Vitamins On Dna And Rna Structures And Dynamics
Éditions universitaires européennes
ISBN13:
9786131554377
$44.21
The important role of vitamins is well known with regard to human health and disease. In this book, we review the effects of vitamins, A, B and C on the structure and dynamics of DNA and RNA. The conjugations of vitamin A (retinol and retinoic acid), vitamin B (folic acid) and vitamin C (L-ascorbic acid) by DNA and tRNA were analyzed. The loading efficacies of these vitamins with DNA and RNA were compared in solution. Vitamins bind nucleic acids via hydrophilic, hydrophobic and H-bonding contacts with vitamin C forming more stable DNA and tRNA adducts. The loading efficacies of these vitamins were from 40% to 60%. Vitamins induce major DNA and RNA structural changes, while biopolymers remain in native conformations.
- | Author: Heidar-Ali Tajmir-Riahi
- | Publisher: Éditions Universitaires Européennes
- | Publication Date: Mar 05, 2019
- | Number of Pages: 88 pages
- | Language: English
- | Binding: Paperback
- | ISBN-10: 6131554374
- | ISBN-13: 9786131554377
- Author:
- Heidar-Ali Tajmir-Riahi
- Publisher:
- Éditions Universitaires Européennes
- Publication Date:
- Mar 05, 2019
- Number of pages:
- 88 pages
- Language:
- English
- Binding:
- Paperback
- ISBN-10:
- 6131554374
- ISBN-13:
- 9786131554377