Stereoselective Total Synthesis of the Natural Oxylipin

In this context, we have developed a simple and straight forward synthesis of the natural oxylipin, (6R,7E,9R,10S)-6,9,10-trihydroxyoctadeca-7-enoic acid. The starting materials were nonanal and 1,6-hexanediol and the key steps were Sharpless kinetic resolution, asymmetric epoxidation and olefin cross metathesis. The reaction steps involved in the present synthesis are lesser compared to those required for the previous one.

• | Author: N. Salvanna
• | Publisher: LAP Lambert Academic Publishing
• | Publication Date: May 07, 2025
• | Number of Pages: 00056 pages
• | Binding: Paperback or Softback
• | ISBN-10: 6208436168
• | ISBN-13: 9786208436162